In many instances, tDCS can be applied directly in a PET/CT without concern for artifact as occurs during EEG or fMRI monitoring. Soterix Medical biomedical engineers work with leading clinical investigators to ensure scanner specific compatibility and trial rigor. For example, when investigators at University of Michigan initiated their landmark study to investigate the actions of tDCS on release endogenous opioids, Soterix Medical provided support on instrumentation designing including ensuring full electrode saturation during extended scanning sessions, custom EASYstrap head-gear for supine resting subjects, and co-registration of imaging and current flow data. Soterix Medical is ready to assist in the rational design of PET and tDCS studies ensuring every experimental confound from subject tolerability and stimulation stability is controlled. Clinical researchers and subjects enrolled in PET studies deserve the best equipment and rational experimental design. As needed, Soterix Medical is on site.
Technical set-up images from DosSantos (2012) study.