High-Definition transcranial Direct Current Stimulation (HD-tDCS) is a transformative technology for targeting cortical structures with weak DC currents. Unlike any other neuromodulation technique, HD-tDCS is non-invasive, targeted, and can leverage the therapeutic potential, convenience, safety, and cost-advantages of tDCS. Soterix is the exclusive manufacturer and provider of HD-tDCS technology.
The HD-tDCS systems and accessories are simple to use and provide clinicians with unparalleled flexibility in the design of targeted electrotherapy. Soterix can work closely with you in determining the optimal strategy for you needs.
High-Definition tDCS was designed to combine the benefits of tDCS, namely low-intensity, safe, and true-neuromodulation with targeting control exceeding Transcranial Magnetic Stimulation. In addition, work by Dr. Michael Nitsche and Dr. Walter Paulus indicates HD-tDCS will produce longer lasting and larger plasticity changes than other neuromodulation modalities. Combined with the ability to robustly sham HD-tDCS using our scalp-slip technique, HD-tDCS provides clinical researchers with a compelling platform.
There are two stimulation modalities to choose from and a range of specialized accessories. The options are designed to provide clinicians with flexibility in achieving optimal solutions. Contact Soterix to discuss your needs and to select an optimal solution.
The Soterix 4×1 Stimulator is the most advanced non-invasive neuromodulation technology. Simple to use, but providing exceptional flexibility, the Soterix 4×1 provides clinicians with previously unattainable specificity and control.
M×N Advanced Systems
M×N HD-tDCS stimulators enables full control of electrode placement and current, producing unprecedented noninvasive targeting.
HD-tDCS 4×1 Adaptor
The 4×1 Multi-Channel interface intelligently divides and guides current generated by a 2-channel device, converting it to HD-tDCS.
Replaces conventional tDCS "pads" with HD-tDCS electrodes. Fully compatible with 1×1 tDCS Stimulators.
Soterix Medical introduces the most advanced non-invasive neuromodulation platform developed: the M×N HD-tDCS stimulators. In 8-channel (8×8) and 4-channel (4×4) models, every M×N system allows full control of electrode placement and current, producing unprecedented noninvasive targeting. Exclusive control technology allows true independent current control and monitoring.
All MXN systems are HD-targets and HD-explore enabled allowing investigators to leverage automatic and manual dose optimization. Combined MXN with Soterix Medical custom modeling for individually optimized treatment.
Leveraging exclusive Soterix Medical HD-electrodes, the MXN system can be configured for effective DC stimulation without sensation in most subjects. Study design benefits from the first full sensation matched sham protocols. Adapt stimulation for susceptible populations and individualize treatment for efficacy and safety.
The Soterix Medical MXN Advanced Neuromodulation platform. The dependable and simple-to-use hardware you expect from Soterix Medical, with the most targeted and adaptable noninvasive targeting software ever. Expect and do more. Contact us to discuss how.
The Soterix 4×1 Multi-Channel Interface converts any 2-channel tDCS stimulator into an HD-tDCS device. The 4×1 Multi-Channel is not a stand-alone stimulator, and during stimulation does not generate any current. Rather, the 4×1 Multi-Channel intelligently divides and guides current generated by a 2-channel device, converting it to HD-tDCS. The Soterix 4×1 Multi-Channel is thus an ideal solution where an existing 2-channel device is already in use.
The Soterix 4×1 Multi-Channel is fully compatible with HD-tDCS accessories and each 4×1 Multi-Channel comes with one connector cable (specify your 2-channel device, if not a Soterix 1x1 tDCS, when ordering).
Soterix provides accessories for HD-tDCS that replaces the “pads” used in conventional tDCS. In fact, HD-tDCS accessories can also be used with Soterix 1×1 tDCS systems. But only when using in combination with HD-tDCS Stimulators can the full potential of HD-tDCS, be achieved.
Contact Soterix to learn more about the right solution to your needs.
Note: Conventional tDCS pads cannot be used with HD-tDCS stimulators. Only approved HD-tDCS accessories can be used with HD-tDCS stimulators.
Two fundamental issues underpin the rational integration of tDCS and EEG: mechanical compatibility and electrical compatibility.
Mechanical compatibility with HD-tDCS: Insertion of large sponge electrodes under an EEG cap will not only block the access of EEG electrodes precisely in the area of interest, but also ejection of fluid from the sponges will shunt neighboring EEG electrodes. Soterix Medical offers a simple and unique solution to tDCS+EEG through the use of High-Definition (HD) tDCS electrodes. Compact in size and gel-based, with validated tolerability, HD electrodes can be inserted between EEG electrodes without compromising mechanical compatibility.
HD electrodes are compatible with any Soterix Medical tDCS or HD-tDCS stimulator. Moreover, Soterix Medical provides HD electrode holders for integration with any commercial EEG headgear including Brain Products (HD1-BP) and Biosemi (HD1-BS). HD-tDCS electrode models are designed to fit existing EEG system adaptor and are the only electrodes validated in multiple clinical trials to produce tolerated stimulation.
WARNING: HD electrodes were developed at The City College of New York and Soterix Medical to allow safe and tolerated DC stimulation. Soterix Medical can no longer provide technical or equipment support for the use of non-validated “small” electrode designs.
Integrate HD-tDCS electrodes (HD-BSM model) with any EEG system. HD electrodes indicated with arrow.
Electrical compatibility with optimized stimulator and rational experimental design: It is not prudent to assume that simple high-pass filtering of the EEG signal will remove confounds from EEG recording. Especially given that DC artifact may be non-stationary due to unknown electrode impedance changes during stimulation and that EEG amplifier active electronics can induce non-linear distortion, Soterix Medical biomedical engineers have developed protocols to implement and validate EEG+tDCS compatibility. It is not prudent to ignore noise that is not measured under the assumption is it not an experimental confound. Note that conventional experimental control arms, such as using sham stimulation or a control-montage, will not in themselves control for EEG+tDCS distortion precisely because the stimulation has been changed (e.g. only the active arm will experience artifact). Soterix Medical’s unmatched technical support is ready to guide you through a straightforward validation process that allows you to use your EEG system of choice.
Noise Comparision between SMI device and Other Commercial Devices