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ResearchFunctional Near Infrared Spectroscopy

Soterix Medical functional Near Infrared Spectroscopy

Redefining the possibilities with functional brain sensing:

Imaging for Tomorrow

Soterix Medical functional Near Infrared Spectroscopy

The NIRSIT system is the first fNIRS system that provides millimeter-level spatial resolution while also providing high temporal resolution (125 ms / 8 Hz). The system defied conventional thinking that fNIRS imaging cannot provide comparable spatial resolution to the more expensive and stationary - fMRI and PET systems. NIRSIT is the culmination of three core/ pioneering technologies: 1) dense packing of laser and photo diodes, 2) code-division multiple access (CDMA) and time division multiple access (TDMA) modulation for high temporal resolution, and 3) monolithic IC implementation for high SNR.

The final product is a first of many things:

  • The first commercial fNIRS system to implement real-time Diffuse Optical Tomography (DOT) resulting in 204 channels that provide 4 mm x 4mm spatial resolution
  • The first truly wireless system (IEEE 802.11 b/g/n) which means users can freely move around while being monitored.
  • The first truly light, portable, and flexible system which means you can carry and wear the system easily and anywhere. Adjustable to brain sizes from children to adults.

The NIRSIT System

  • Ground breaking joint optimization of system level architecture, circuits and signaling schemes.
  • Single IC system for high SNR and size efficiency.
  • Light (500 grams), compact, and portable: Just grab and go.
  • Easy-to-use: Just follow step-by-step instructions on the tablet app.
  • Easy-to-setup: Gain calibration < 1 min.
  • Wireless: No wires means that users can freely move around within the range of the network.
  • Unmatched Performance: photogrammetry for localization, 6-axis gyroscope and proprietary algorithm for motion artifact removal, save, retrieve and play back data using tablet provided or any computer.
NIRSiT System

The NIRSIT Software

Analysis and Post Processing

Proprietary analysis tool that is easy-to-use and includes typical fNIRS analysis:

  • Signal processing with band pass filter and motion artifact removal algorithm
  • 2D and 3D activation maps
  • Block averaging and feature extraction
  • GLM and SPM analysis
NIRSiT Software - Analysis and Post Processing

Task Mode

Monitor the level and distribution of subject’s cerebral oxygen saturation while performing pre-programmed tasks (cognitive and behavioral).

NIRSiT Software - Task Mode

Monitoring Mode

Perform real-time cerebral oxygen saturation monitoring in either: 3D mode (monitor HbO2, HbR or HbT on a 3D brain model) or Time Series mode (monitor Hb02 and HbR changes in a transient graph)

NIRSiT Software - Monitoring Mode

Application Areas

  • Neuro-Rehabilitation: Cognitive tasks are typically used in rehabilitation programs to either help in function restoration or learning how to do things differently when function cannot be restored. Monitor progress of rehabilitation strategy by tracking performance gain over time.
  • Depression and PTSD: Those affected by Depression and PTSD are commonly assessed for delayed verbal and figural memory, attention and learning. Monitor symptom progression by checking signs of emotional reaction to specific stimulation.
  • Concussion: Various tests and tools are employed to assess cognitive and neuropsychological changes post-concussion. In combination with assessment tools, monitor concussion event effects by checking signs of cognitive impairment.
  • Education: Monitor progress by checking cognitive performance when performing cognitive and behavioral tasks - for instance by comparing left and right hemisphere brain activation.

NIRSIT by OBELAB is exclusively distributed in the US by Soterix Medical.

Caution! Investigational Device. Federal (or United States) law limits device to investigational use.

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