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Soterix Medical 1x1 Platforms

The 1x1 platform is the most state-of-the-art, customizable, and reliable platform for pad-based Transcranial Electrical Stimulation. The 1x1-tDCS, 1x1-tES, and 1x1-CT devices provide unique outcomes as a result of: 1) 11 years of device innovation and optimization; 2) Open-Panel controls; 3) LTE power management, and 4) Best-in-class accessories. Modular, reliable, and fully compatible series of non-invasive electrical brain stimulation devices and accessories. The most precise and reproducible systems, customized to your trial.

Soterix Medical 1x1 tDCS Device and EASYstrap

Soterix Medical devices provide unique performance as these products, the methods of manufacturing are the subject to one or moreU.S. or foreign patents or pending applications including but not limited to US9956395B2, US8818515B2, US8718778B2.


Unique outcomes driven by industry leading innovation

For over a decade, 1x1 platforms have introduced industry leading features that enhanced reliability, usability, and rigor. Soterix Medical products remain the choice when quality cannot be comprimised with outcomes that are specific to quality of these features.

1x1 tDCS: first device engineered for tES practices

Introduction of LTE power management

TrueCurrent and SMARTscan features set standards for reliability of use

EasyPads: First electrodes designed for tDCS/tES

EasyStrap: first head-gear to support reliable placement of pad electrodes.

Modeling driven dose with HDexplore software

1x1-CT: First device optimized for true double-blind trials

SnapPad electrodes set standard for easy-of-use and reliability

SnapStrap: Automatic pad positioning and securement

Verified MRI and PET Compatibility

Extension of dose to 5 mA leveraging LTE and SnapPads

ElectraRx: An online session management portal


Better neuromodulation starts with better stimulators

The 1x1 platform stimulators are the most precise stimulators ever made for non-invasive electrical stimulation, including unique control features not available on any other products.

Better technology means better outcomes. Soterix Medical believes that in advanced neuromodulation one size does not fit all, the 1x1 platform includes five stimulator devices, upgradable adaptors, and state-of-the-art accessories customizable to your needs.

Designed for Neuromodulation. Customized for your trial.

In advanced neuromodulation “one size does not fit all”. A single design that tries to achieve everything, compromises everything leaving subjects at risk. Soterix Medical devices and accessories allow simple configuration and customization.
Soterix Medical is the trusted leader in tDCS and related technologies because we provide clinicians and investigators with the only accessories designed for tDCS/tPCS/tACS/tRNS.

Conventional tDCS uses one anode and one cathode (1x1) with tremendous possibilities for customization and optimization. The Soterix Medical 1x1 line of stimulators provides clinicians with the right solution. The selection of the right stimulator for your objectives is central for rational tDCS.

  • LTE Enabled
    Adaptive ramp-up stimulation technology to limit the required voltage for tDCS.
  • SMARTscan
    Continuous visual indication of electrode quality before and during stimulation.
  • True Current
    Clearly indicates the actual current supplied at the moment.
  • Tickle
    May be used to supply a very weak current prior to tDCS to help condition the skin.
  • Relax
    Allows the clinician to use a simple sliding bar to transiently decrease the current from the pre-set value, for example, based on subject feedback.
  • Duration up to 40 mins
    Stimulation duration can be adjusted on each session using a simple dial.
  • Intensity up to 5 mA
    Easy adjustment of stimulation intensity.
  • Industry Standard for transcranial Direct Current Stimulation (tDCS). Stimulation technology that sets the Gold Standard.
  • The most trusted and validated device in tDCS upgraded with LTE and Adaptive Current to 5 mA.
  • Explore 1x1 tDCS »
  • LTE Enabled
    Adaptive ramp-up stimulation technology to limit the required voltage for tDCS.
  • SMARTscan
    Continuous visual indication of electrode quality before and during stimulation.
  • True Current
    Clearly indicates the actual current supplied at the moment.
  • Tickle
    May be used to supply a very weak current prior to tsDCS to help condition the skin.
  • Relax
    Allows the clinician to use a simple sliding bar to transiently decrease the current from the pre-set value, for example, based on subject feedback.
  • Duration up to 40 mins
    Stimulation duration can be adjusted on each session using a simple dial.
  • Intensity up to 2 mA
    Easy adjustment of stimulation intensity.
  • The 1x1-tES device is the most sophisticated and precise stimulator ever designed for tDCS, tACS, tPCS, and tRNS.
  • The best option for research labs that want the flexibility to test across tES waveforms with the established reliability and precision.
  • Explore 1x1 tES »
  • LTE Enabled
    Adaptive ramp-up stimulation technology to limit the required voltage for tDCS.
  • SMARTscan
    Continuous visual indication of electrode quality before and during stimulation.
  • Double Blind
    Clinician and patient blinded study for unbiased results.
  • SMARTscan Plus
    Continuous visual indication of electrode quality before and during stimulation without compromising blind.
  • Pause
    Stop stimulation during a session and resume later to complete the session.
  • Duration Custom
    Stimulation duration can be adjusted on each session using a simple dial.
  • Intensity Custom
    Easy adjustment of stimulation intensity.
  • Full multicenter clinical trial support with subject specific codes. Customized stimulation devices, for your clinical trials.
  • Arbitrary waveforms including tDCS, otDCS, tACS, tRNS are available for customized clinical trial solution.
  • Explore 1x1 CT »

Four design principles of Open-Panel™ Device Interfaces

To understand the Soterix Medical's Open-Panel interface, one needs to consider how tES and tDCS are applied in the best clinical and academic centers. The risk of relying on a wireless connection with a computer to control and monitor the device is not acceptable. Similarly, complex and hidden drop-down menus create inherent risk in programming mistakes. A single mistake can compromise subject safety and the integrity of an entire clinical trial. For medical grade equipment, device status and subject monitors should be clearly visible on the device display. Soterix Medical devices, including features such as Open-Panel, are chosen when patient tolerability and trial integrity cannot be compromised.

Open-Panel™ Reproducibility Advantage

Soetrix Medical 1x1 Device Open Panel No drop down menus. No hidden setting.

No drop down menus.
No hidden setting.

Avoid confusion and mistakes. Save time. 1x1 devices can be programmed in seconds with simple switches and controls.

Soetrix Medical 1x1 Device Open Panel No external computer. All devices stand alone.

No external computer.
All devices stand alone.

With stand-alone 1x1 stimulators, there is never a need to use a personal computer for interface. This reduces your cost, complexity and potential errors.

Soetrix Medical 1x1 Device Open Panel Elevated panels. Backlit displays.

Elevated panels.
Backlit displays.

Easy to read displays, even at a distance and even in reduced light conditions, means you always can monitor stimulation status.

Soetrix Medical 1x1 Device Open Panel Optimized devices. Customized interfaces.

Optimized devices.
Customized interfaces.

In advanced neuromodulation, one size does not fit all. Display and control items are minimized to what you need. Clarity and simplicity without compromise.


Open-Panel™ Safety Advantage

A single programming error undermines reproducibility and safety of an entire trial. Open-Panel reduces errors even under multiple-user or high-throughout conditions.

No risk of computer or connection failure leading to loss of device control. Risks associated with computer failure (e.g. during a software update) are avoided.

Device settings and current state are always visible to their operator. Intelligent SmartScan testing provides early warning of poor contact conditions.

Devices prevent current transients even under unexpected conditions such as sudden re/dis-connection. Soterix Medical is the trusted leader in tES by designing safety factors for the unexpected.

Simple to use

Open-Panel™

In developing the 1x1, feed-back from leading clinical centers was clear: stimulation must be simple to program and its status must always be apparent to the investigator. With easy-click control knobs to set stimulation duration and intensity, and back-lit status displays visible in dim or bright room light, the Soterix Medical Open-Panel™ design takes the guess work out of the stimulation.

No drop-down menus. No hidden settings. No external computer.

Design for simple and clear clinical trials with Soterix Medical Open-Panel™.

Exclusive Soterix Device Features

Each Soterix Medical 1x1 feature was developed by our team of biomedical engineers consulting closely with leading clinical centers. Designed to simply set-up, provide intelligent warning of a fault condition, and allow for adjusting for patient comfort - these features facilitate reliable and tolerated tDCS. The Soterix Medical SMARTScan™ feature is central in all tDCS devices to allow reliable set-up and monitoring.

Provides a continuous visual indication of electrode quality before and during stimulation.

From pre-stimulation set-up, to during stimulation monitoring, to post-stimulation confirmation, the Soterix Medical SMARTScan™ feature provides an intuitive and clear indication of electrode contact quality. Use the SMARTScan™ during set-up to adjust electrodes and head-gear for optimal fit. During stimulation, SMARTScan™ provides a constant indication of electrode quality and can be monitored during adjustments (e.g. addition of saline to drying electrodes). After stimulation, SmartScan™ confirms a successful trial. Because “resistance” is not meaningful for tDCS, SMARTScan™ was developed by Soterix Medical engineers to provide clinical investigators with a simple-to-read indication of contact quality.

Clearly indicates the actual current supplied at the moment.

What other devices promise, the 1x1 tDCS delivers. The back-lit display can be monitored during stimulation ramp up to confirm that the targeted current intensity is achieved.

May be used to supply a very weak current prior to tDCS to help condition the skin.

Tickle™ may be used to condition skin prior to tDCS and for naïve subjects who are anxious about stimulation. A custom on-off waveform pattern generates mild and brief sensation under electrodes.

Allows the clinician to use a simple sliding bar to transiently decrease the current from the pre-set value, for example, based on subject feedback.

Based on feed-back from leading clinical centers, Soterix Medical exclusive feature, RELAX™, accommodates subjects who may be anxious when stimulation is initiated or during the course of stimulation. The Relax™ slider may be adjusted from full to reduced intensity based on subject perception without interrupting or aborting stimulation.

For susceptible subjects, Limited Total Energy minimize power and energy delivery

Limited Total Energy for tDCS (LTE-tDCS) was developed exclusively by Soterix engineers. LTE limits the voltage and power required for tDCS through the use of adaptive ramp-up stimulation and intelligent energy management for currents up to 1.5 mA.

Simple and intelligent sham waveforms.

An automatic stimulation sham feature that is engaged with a simple switch. Auto-sham automatically calculated and produces a sham waveform based on the indicated “real” waveform. For example, for a corresponding real waveform of 1.5 mA and 10 minutes. auto-sham will provide a ramp up/down to 1.5 mA at the start of of stimulation, and again after 10 minutes, with the timer automatically adjusted such that the total run time us exactly matched to the real case. Based on the Soterix Medical Open-Panel™ design principle: with no complicated programming or hidden drop-down menus required.

Full integrated clinical trial support with subject codes and customized sham protocols

Developed to support multi-center clinical trials in tDCS. Double Blind from Soterix optimize well beyond traditional ramp up/down shams. For true operator blinding, device operation must balance providing a continuous indication of stimulation and electrode quality status for safety, without betraying whether the stimulation session is real or sham. Since “one size does not fit all,” Soterix Medical scientists work with you to customize Double Blind to your active protocol and electrode montage.

A simple feature that minimizes dropout in double-blind clinical trials

Sometimes trivial issues require stimulation interruption or adjustment. Rather than abort a session which can result in subject exclusion or data confounds, the PAUSE feature was developed in collaboration with clinical trial experts running higher-volume or longer duration trials. For both automatic (under SMARTScan) and user initiated PAUSE, this exclusive feature intelligently avoids breaking sham even in double-blind trials.


Fully compatible and expandable with all Soterix
Medical 1x1 accessories

Fully compatible and expandable with all Soterix Medical 1x1 accessories

Every 1x1 accessory is optimized for simple and consistent set-up, robust and safe performance, and ease of use. Since "one size does not fit all" in tES, the 1x1 accessory set provides the flexibility to optimize performance. From EASYpads™ to EASYstraps™ Soterix Medical 1x1 accessories are designed and validated specifically for the 1x1 platform. Our scientific team is ready to help you select the best accessory set to make your 1x1 the most optimized platform adjustable to any application.

1x1 tDCS Accessories »


Limited Total Energy™ (LTE)

Limited Total Energy for tDCS (LTE-tDCS) was developed exclusively by Soterix engineers. LTE limits the voltage and power required for tDCS through the use of adaptive ramp-up stimulation and intelligent energy management for currents up to 1.5 mA. Soterix Medical LTE enabled devices include the most advanced transient protection in the industry, an electrode becoming temporarily disconnected, for example due to subject movement. In addition, should resistance increase to atypical levels, LTE-tDCS will automatically reduce the applied current so as to maintain a low voltage.

Soterix Medical tDCS-LTE Device

Soterix Medical tDCS-LTE is a unique system that provides an additional safety margin, without compromising efficacy, when stimulating susceptible subjects.

Our scientific team is ready to work with you to determine optimal dose parameters and accessories.


Proven to Limit Power During tDCS

The difference between conventional tDCS and tDCS-LTE is that conventional tDCS applies a fixed ramp slope while tDCS-LTE varies ramp intensity to limit power delivery. Soterix tDCS-LTE also limits power transients that might occur during tDCS due to sudden changes in resistance. tDCS-LTE further enhances abort-protection features already enabled on all Soterix 1x1 devices. Finally, tDCS-LTE alerts the operator when a high-power condition occurs and automatically activates LTE to reduce power consumption.

Our scientific team is ready to work with you to determine optimal dose parameters and accessories.


Expert support and target modeling

Researchers and clinicians choose Soterix Medical products knowing that they are backed by the most experienced neuromodulation engineers, regulatory staff, and clinical trial design consultants. Soterix Medical was founded with one mission: to advance the science of neuromodulation. We are your partner every step of the way.

Only HD-Explore™ for tDCS allows you to simulate any tDCS montage, not just a sub-set, on a range of standard head or custom loaded head models. But consistent with our Open-Panel™ design principles , HD-Explore™ software is stand-alone from hardware, available when you need it and not when you don't.

State-of-the-art software driven control and modeling

Soterix Medical Neurotargeting Software allows the user to stimulate any transcranial Electrical Stimulation montage. You decide the number of electrodes and current intensity. Simply position the electrodes relative to the EEG 10/10 (70+ scalp locations) system or a dense concentric system (300+ scalp locations), thereby allowing inclusion of intermediate scalp or neck positions. Use our standard head library or import your own anatomical scans. Arbitrary electrode montages and head models: exclusively from Soterix Medical Neurotargeting Software.

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Caution! Investigational Device. Federal (or United States) law limits device to investigational use.