HD-Explore software

The most advanced and intuitive software to simulate brain current flow during tDCS, tES, HD-tDCS and HD-tES

HD-Explore™ is protected by patents, other intellectual property rights, patents pending or other intellectual property rights pending.

Easy to use software without compromising accuracy

HD-Explore™ is the only stand-alone modeling software that provides predictions of brain current flow with equivalent accuracy to the most advanced engineering software. The reason is a breakthrough in how models are solved based on the principles of linearity and super-position. The result is that Soterix Medical HD-Explore™ is able to provide performance comparable to a team of engineers working with a super-computer for days, using a laptop in just minutes.

HD-Explore™ is the only research grade software used in hundreds of research publications including:

The same breakthrough that allows instant current flow solutions making HD-Explore™, the only software that can do simulation for any tDCS, tES, HD-tDCS and HD-tES montage.

Performance verified against COMSOL Multiphysics and Abaqus

Easy to use and intuitive interface, with just three steps to a complete answer


Select a head from the Soterix Medical library
Adult, pediatric, stroke, and custom models.

HD-Explore Head Stack


Select the HD or EASYpad electrode montage.

HD-Explore Electrode layout
HD-Explore Electrode layout


Visualize current flow through the head in 2D and 3D layout.

3D Current Flow Visualization

3D Current Flow Visualization

Cutting Planes

Cutting Planes

Line Export

Line Export

Sphere Export

Sphere Export

Flexibility and individualized modeling capability makes Soterix Medical HD-Explore a modeling tool-box to build on

Included in HD-Explore

Standard MNI head and three adult heads.

Standard MNI 152 and one Adult head below.

Individual modeling

Upload your MRI to our server and the model is downloaded straight to your HD-Explore license

Separate purchase required.

Acquire additional heads from the SMI library

Stroke (varied lesions)
Low/high BMI
Skull defects

Separate purchase required.

Accuracy validated in primates and non human primate subjects and equivalent performance to research grade software

Models are only as valuable as they are validated. The parameters used in HD-Explore are based on extensive validation in human subjects and non-human primates, making HD-Explore the most trusted stand-alone current flow modeling software.

Soterix Medical Case Use 3

Understanding Semantic Integration with targets High-Definition tDCS

Soterix Medical Case Use reports are provided for information purpose only and the original publications should be consulted for comprehensive details.

Caution! Investigational Device. Federal (or United States) law limits device to investigational use


Neurotargeted Montage:

Using Soterix Medical’s exclusive Neurotargeting software, HD-Explore, research optimized High-Definition tDCS to target the angular gurus. High-Definition tDCS, an exclusive Soterix Medical Technology, uses HD electrode arrays to maximize brain targeting. Here, researchers at the University of Pennsylvania were able to designed a 4x1 montage that maximizes targeting. HD-Explore is simple to use and runs on a conventional laptop, yet the results are compatible to state-of-the-art computational lab approaches.


Rigorous Science:

Published in the Journal of Neuroscience, the University of Pennsylvania teams discover a causal role of the left angular gyrus in lexical-semantic integration which provides motivation for novel therapeutic applications in patients with lexical-semantic deficits. This discovery is only possible using focal HD-tDCS which is the only target and sub-threshold neuromodulation approach. Only though targeted and specific neuromodulation could the the angular gyrus have been isolated. Conventional tDCS lacks the focality needed for angular gyrus stimulation and TMS will lead to supra-threshold secondly activation.


Real Impact:

Several news agencies highlight both the scientific and clinical impact of this work including Science Daily and John Hopkins News. The combination of scientific innovation and state-of-the-art technology (Soterix Medical HD-Explore and HD-tDCS) make this work foundational. Because a brain region was directly implicated using targeted sub-threshold neuromodulation, the work establishes a foundation for ongoing exploration of brain function and treatment options.

Soterix Medical was founded to support the rigorous science and medicine of non-invasive neuromodulation

License Options

HD-Explore comes in three editions: Standard, Premium, and Pro. They share common features, but Premium and Pro have additional features.


Features License Type
Pro Premium Standard
Custom Modeling Solutions
3 Adult Heads + 1 MNI 152 Head
3D view of segmentation masks of all tissues
3D solid surface and transparent surface views of current flow
Cutting plane and opacity functions for enhanced visualization and post-processing
Compatible with all Soterix Medical HD-tDCS/tES and 1x1 tDCS/tES devices
Model any tDCS, tES, HD-tDCS or HD-tES montage
Validated parameters
Export electric field intensity values for post processing
Extra-cephalic electrodes for tDCS/tES montages
Flexibility to save tDCS/tES and HD-tDCS/HD-tES montages
Export high resolution 3D images
Perpetual License and free upgrades to the latest version for the lifetime of the product
Lifetime technical support
5 individualized custom head models* Available for purchase
10 additional individualized custom head models* Available for purchase Available for purchase

* High resolution MRI scans are needed

Caution! Investigational Device. Federal (or United States) law limits device to investigational use.